Inferring Continuous and Discrete Population Genetic Structure Across Space
نویسندگان
چکیده
منابع مشابه
Inferring continuous and discrete population genetic structure across space
1 Department of Integrative Biology, Ecology, Evolutionary Biology, and Behavior Graduate Group, Michigan State University, MI 48824 2 Center for Population Biology, Department of Evolution and Ecology, University of California, Davis, CA 95616 3 Institute of Ecology and Evolution, Departments of Mathematics and Biology, University of Oregon, Eugene, OR 97403 a [email protected]; b gmcoop@ucdavi...
متن کاملInferring network structure in non-normal and mixed discrete-continuous genomic data.
Inferring dependence structure through undirected graphs is crucial for uncovering the major modes of multivariate interaction among high-dimensional genomic markers that are potentially associated with cancer. Traditionally, conditional independence has been studied using sparse Gaussian graphical models for continuous data and sparse Ising models for discrete data. However, there are two clea...
متن کاملDiscrete-space versus continuous-space lesion boundary and area definitions.
Measurement of the size of anatomic regions of interest in medical images is used to diagnose disease, track growth, and evaluate response to therapy. The discrete nature of medical images allows for both continuous and discrete definitions of region boundary. These definitions may, in turn, support several methods of area calculation that give substantially different quantitative values. This ...
متن کاملOn inferring and interpreting genetic population structure - applications to conservation, and the estimation of pairwise genetic relatedness
The presence of population structure is ubiquitous in most wild populations of species. Detecting genetic population structure and understanding its consequences for the evolutionary trajectories of species has shaped a lot of our understanding of the process of evolution. This delineation of subdivision within a population plays an important role in several allied fields, including conservatio...
متن کاملModeling Genetic Regulatory Networks: Continuous or Discrete?
Selecting an appropriate mathematical model to describe the dynamical behavior of a genetic regulatory network plays an important part in discovering gene regulatory mechanisms. Whereas fine-scale models can in principle provide a very accurate description of the real genetic regulatory system, one must be aware of the availability and quality of the data used to infer such models. Consequently...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Genetics
سال: 2018
ISSN: 1943-2631
DOI: 10.1534/genetics.118.301333